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Insulin growth factor 1 receptor-mediated pro-oncogenic signaling has been demonstrated in multiple cancers and molecular mechanisms leading to dysregulation of IGF-1R has been an intense focus of cancer research

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140 This may involve determining the chemical properties of Gln antagonists suitable for ferritin binding and achieving stable drugloading systems at the nanoscale

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One of the first applications of FCS in structural IDP analysis was reported in 2006, when Crick et al