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Thus, glutathionylation of roGFP2 WT (SH) 2 was most likely rate-limiting before the intramolecular disulfide bond was rapidly formed

10.1186/s13287-021-02392-9 176 ZafardoustS.KazemnejadS.DarziM.Fathi-KazerooniM.RastegariH.MohammadzadehA

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Carl Zeiss LSM 780 Confocal Microscope (from Optical Imaging and Vital Microscopy Core at Baylor College of Medicine)

However, more researches need to be conducted in order to investigate how much time is needed for skin color to return to its original state following drug withdrawal