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In vivo studies Experimental work Animals were maintained under specific-pathogen-free conditions and in compliance with the Northern Ireland Department of Health (under PPL 2874 and 2960) regulations with approval from the QUB Animal Welfare and Ethical Review Body

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Allocation, randomisation and blinding The randomised allocation list was generated in STATA (Stata, College Station, TX) using the script randomize (net from We randomised the women in a 1:1 ratio in blocks of 8

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10.1046/j.1365-2605.2000.00250.x 38 PunabM.PoolametsO.PajuP.VihljajevV.PommK.LadvaR.et al (2017)