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After opening, aseptic handling techniques must be followed to maintain sterility

For timing and protocol structure, many research-style references favor once-daily subcutaneous administration in the evening , often 3060 minutes before sleep , to better align with normal nocturnal GH pulses

Most are shipped as a lyophilized (freeze-dried) powder, which is the most stable form for long-term storage

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Unfortunately, we cannot make any inference as to the possible reasons for these differences in observations due to the limitations of the cross-sectional study design