A comprehensive panel of primary antibodies was used to detect various proteins: FOXO4, p53, Ser15-phospho-p53, p21 (cyclin-dependent kinase inhibitor 1A), p16 (cyclin-dependent kinase inhibitor 2A), 3-HSD, CYP11A1, CYP17A1 (cytochrome P450 family 17 subfamily A member 1), and several senescence-associated secretory phenotype (SASP) factors including IL-1, IL-1, IL-6, IL-10, TNF-, and TGF-
Thousands of published studies document its effects across multiple conditions
Collectively, several lines of evidence suggest that p53 acts as a catabolic break upon IF, which is released through adipocyte-specific ablation of p53 signalling in obese mice
Zarrouk, M., Marzouk, B., Ben-Miled, D
CHAIKOFF, The temporary nature of the inhibitory action of excess iodine on organic iodine synthesis in the normal thyroid
The compiled studies in this Review will contribute to the exploration of the prominent causes of idiopathic male infertility