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Shahrbaf MA, Akbarzadeh MA, Tabary M, Khaheshi I (2021) Air pollution and cardiac arrhythmias: A comprehensive review

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These compounds increase cell permeability and inhibit the activity of selected membrane enzymes/transport proteins, but they can also induce COX-2 expression in macrophages (87)

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Previous studies have shown that the Box1 motif, although required for JAK binding, is not sufficient to determine the specificity for a particular JAK to associate with its cytokine receptor, and that additional sequences in the receptor play an important role in specificity since JAK1 and JAK2 were shown to have different preferences for GHR, EPOR, and GP130 chimeras (70)