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Treating these issues requires a careful B12 dosing plan

Sometimes you need higher doses despite adequate numbers because functional improvement requires B12 levels well above the bare minimum for preventing deficiency

Some patients tolerate gradual adjustments better than aggressive protocols

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Because this formula contains niacinamide, a few people might experience a flushing reaction (warmth, redness of the skin) or slight itching, although niacinamide usually does not cause the intense skin flush that niacin (nicotinic acid) does

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