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Gclc L-KO mice showed no overt histological signs of liver damage (Fig

60 In a clinical trial in which 47 subjects with papulopustular rosacea treated one side of their face with a tea tree oil-enhanced 2.5% permethrin gel and the other with placebo twice daily for 12 weeks, tea tree oil plus permethrin was more effective at reducing mite count on the skin and improving rosacea symptoms

This is why more isnt always better with vitamin C and why very high concentrations dont necessarily give extra benefits

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These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione