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They chose to study melanoma because the incidence of melanoma is increasing in the United States and Europe, melanoma cells are sensitive to oxidative stress, and a good mouse model of melanoma already exists, Dr

They found that PCs not only reduce oxidative stress in damaged skin via Nrf2 activation but also stimulate capillary formation and facilitate endothelial progenitor cell migration to the wound site, thereby accelerating wound healing and promoting neoangiogenesis

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