Medical-grade skincare (prescription retinoids, vitamin C, SPF)
Melatonin is found in various tissues other than the pineal gland, involving the pancreas, liver, brain, lens, thyroid, and others (Mahmood 2019)
The area below your ribs and above your hip bone, at least 2 inches away from the belly button, is the best choice
Over the last 5 to 10 years, peptides have gone from something only performance athletes, biohackers, and longevity doctors talked about to something you hear about casually in group chats and on TikTok
Journal of Allergy and Clinical Immunology 140(1):109120
Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: urinary retention pruritus, rash constipation Pharmacokinetics: taken orally by tablet, 75 mg once daily hepatic metabolism predominantly by CYP3A4 vibegron does not inhibit CYP2D6 (unlike mirabegron), so its pattern of drug interactions differs from mirabegron vibegron is a P-gp substrate half life ~31 hours Drug Interactions: increases digoxin Cmax (21%) and AUC (11%) Notes: Vibegron is a newly approved drug, and the estimated Walmart cost for Gemtesa oral 75mg tablets is ~$485 for a supply of 30 tablets (GoodRx.com
