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Key points Increased intestinal permeability occurs in a wide range of disorders, including inflammatory bowel disease, coeliac disease and graft-versus-host disease, but the relative contributions of barrier dysfunction and immune responses are unclear

Prediction of thyroid C-cell carcinogenicity after chronic administration of GLP1-R agonists in rodents (Toxicology and Applied Pharmacology)

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The terminal aminohexanoic amide moiety further extends the aliphatic region, modifying polarity distribution across the molecule