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Regarding the direct action of EDCs on the thyroid gland, major targets seem to be the sodium/iodide symporter (Na + /I symporter, NIS), responsible for the active transport of iodine to the thyroid, and thyroperoxidase (TPO), the enzyme indispensable for thyroid hormone synthesis, but EDCs can disturb each step of hormonogenesis [24, 25]

These findings are mechanistically plausible and directionally useful, but they do not constitute human clinical evidence

doi: 10.1186/s12936-019-3075-5 13 DingY.DingC.YeN.LiuZ.WoldE

How Long Does a Session of IV Therapy Last