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Above that, molecules have a genuinely harder time crossing the gut lining into circulation

S2CID 24097516

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the higher taxonomies from five key families in the Lop group were Tannerellaceae , Sutterellaceae , Eggerthellaceae , Clostridiaceae and Anaerovoracaceae

But they come with significant drawbacks: high cost, injection site reactions, increased infection risk due to immune suppression, and the development of anti-drug antibodies over time that can reduce efficacy