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From mice to men: insights into the insulin resistance syndromes

Think of it as investing in your skin's foundation rather than reaching for a short-term smoothing effect

Even though alternative models are available, such as animal models or ex vivo models, in vitro models offer higher experimental flexibility and reproducibility, making them a valuable tool for the understanding of pathophysiological mechanisms of several diseases, such as CVDs

half-life: ~30 min2 hours Plasma levels decline ~60% with age (~200 ng/mL at age 20 ~80 ng/mL at age 60) Influences expression of ~31% of studied human genes linked to repair and regeneration Stimulates collagen type I and III synthesis by up to 70% in studied models Activates fibroblasts

Sviridov, A

Ciprofloxacin-induced phototoxicity in an adult cystic fibrosis population