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Although BSO is the most utilized treatment to achieve GSH depletion, other strategies such as inhibition of cysteine/glutamate transport showed a synergistic effect in combination with gemcitabine for inhibiting proliferation of pancreatic cancer cell lines[50]
BPC-157 + SS-31 Combines mitochondrial protection with cellular repair for enhanced recovery
Quantitative reverse transcription PCR (RT-qPCR) Total RNAs were extracted from Swan 71 cells, human villous tissues, and mouse placental tissues using Trizol (Invitrogen, Carlsbad, USA) 120,121
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Multiple endocrine neoplasia syndrome type 2 carries similar restrictions