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Metal-Mediated Signaling: Delivers bioavailable Cu to copper-dependent enzymes and pathways (e.g., lysyl oxidase family) that participate in cross-linking and tissue architecture

Collagen Synthesis and Tendon Matrix Repair Tendons are made largely of collagen fibers, especially type I collagen

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Studies also reveal that doxorubicin enhances the expression of SASP, thereby inducing inflammatory states in p16-3MR cells [60]

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