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Key Specs Research context: NNMT interaction, enzyme and pathway assays Common model types: biochemical assays, cell-based pathway studies References: PubChem and PubMed [1,2] Referenced Citations PubChem, 5-Amino-1-methylquinolinium: PubMed, NNMT and metabolic regulation (review and mechanistic context): NNMT Interaction Studies 5-AMINO-1MQ is primarily examined for its inhibitory interaction with NNMT, an enzyme involved in nicotinamide methylation and NAD-related metabolism [1,2]
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(2013) demonstrated that minor amino acid substitutions in AtGLR1.4 suppressed ligand-gated channel activity when expressed in Xenopus oocytes, and these residues are conserved across multiple AtGLRs
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