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Reported adverse reactions include nausea, difficulty breathing, and, in rare cases, serious conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and renal dysfunction

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This hypoxic state stabilizes hypoxia-inducible factor (HIF-1), a crucial transcription factor mediating the protective effect of SCFAs

On the other hand, ARID2 (a subunit of PBAF) in SMARCB1-rescued cells (+ SMARCB1) localized only to the region proximal from the TSS of the SLC7A11 locus (Fig

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Laboratory tests revealed increased white blood cell and neutrophil count, but no eosinophil count