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It has been demonstrated that Epitalon has a direct influence on melatonin synthesis [15], alters the mRNA levels of interleukin-2 [16], modulates the mitogenic activity of murine thymocytes [17], and enhances the activity of various enzymes, including Acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) [18] and telomerase [19]

INDICATIONS AND DIAGNOSIS Typically, a subacromial injection is performed after a trial of more conservative therapy

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