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It enhances the expression of growth factors, which are crucial for tissue repair and regeneration
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For each E46 case, assess whether clinical indicators (weight loss %, albumin, prealbumin, muscle wasting, intake documentation) support upgrading to E44.0 or E43
Lancet 359:20532058 Belch J, Hiatt WR, Baumgartner I, Driver IV, Nikol S, Norgren L, Van Belle E, Committees T, Investigators (2011) Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia
Shaking creates thousands of tiny air bubbles that violently batter the peptide molecules, accelerating denaturation