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Trial designs that implement inductionmaintenance sequences, co-primary mechanistic and clinical endpoints, longer follow-up for durability, and head-to-head comparisons under harmonized outcome sets are priorities

Glutamate functions as a classical neurotransmitter (Shepherd, 2004

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2020, doi:10.3390/molecules25030609

The emergence of dihydroorotate dehydrogenase (DHODH) as a therapeutic target in acute myeloid leukemia

Supporters point to a large real-world usage record with few reported problems