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Konopleva M, Marini F, Leysath C, Champlin R, Andreeff M , Korbling M

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Weight of evidence: Overall evidence is Low-Moderate: multiple animal studies and a growing number of small clinical trials suggest benefits across gutbrain signaling, social and behavioral domains, gastrointestinal symptoms, and neurophysiological patterns, yet most human studies rely on caregiver-reported outcomes, lack biomarker integration, and seldom control for diet, comorbidities, or baseline microbiome composition

PubMed: 10999493 Ipamorelin Improves Body Composition in Healthy Adults human pilot Svensson J, Johannsson G, Bengtsson BA, et al

This makes provider review, product sourcing, dosing, and monitoring especially important

We think this needling causes micro-injuries leading to tendon healing and remodelling