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The nitric oxide generated through this pathway promotes vasodilation, inhibits platelet aggregation, and enhances endothelial cell survival while supporting the formation of patent, functional vessels
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217,218 The mitochondrial sirtuin-related acetylome covers almost all the mitochondrial metabolism, including the enriched SIRT3-related TCA cycle, ETC, FAO, the SIRT4-associated anion transporters, the translation and energy metabolism, the SIRT5-regulated TCA cycle and branched chain amino acid catabolism (BCAA) metabolism
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