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Composition Active Agent: Benzyl Alcohol 0.9% (bacteriostatic preservative) Base: Sterile Water Volume: 10ml or 30ml per vial (select above) pH: 4.57.0 Container: Sealed glass vial with rubber septum and aluminium crimp cap Manufactured in: Boecillo (Valladolid), Spain ISO 13485:2016 + GMP + ISO 9001:2016 certified facility Intended use: Research Use Only (RUO) not for clinical use In-use period: Up to 28 days after first puncture with aseptic technique Storage Store unopened vials at room temperature (15-25C)

Cellular signalling mechanisms

This decline is partly due to changes in the bodys ability to synthesize the amino acids required for glutathione production and increased oxidative stress with age

As expected, we observed limited expression of DE genes in the hiPSC line CRL S23 under all conditions, confirmation that this line was recalcitrant to differentiation to DE

[7] Frias, J.P., et al