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315 Notably, although tenofovir disoproxil fumarate treatment can significantly alter the gut flora of HBV-infected individuals, it failed to fully restore it to a healthy state, and serum inflammatory cytokine concentrations did not improve significantly, suggesting that treatment duration may affect flora recovery and inflammation remission
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These approaches may act through multiple pathwayssuch as modulating the gut microbiota, regulating immune responses, and enhancing metabolic functionsthus offering novel therapeutic avenues for ASD ( 4.1 Gluten-free and casein-free diets The gluten-free and casein-free (GFCF) diet is among the most widely implemented nutritional interventions for ASD, based on the hypothesis that opioid-like peptides derived from gluten and casein may affect brain function (nal et al., 2023)
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