Tomat AL, Inserra F, Veiras L, Vallone MC, Balaszczuk AM, Costa MA, et al
Chronic wounds are typically covered with inflammatory exudates and biofilms 25 , which constitute a physicochemical barrier hindering the penetration of topical therapeutic agents into the underlying live tissues
The Broad Institute gene expression data is particularly compelling because it was generated through an unbiased, genome-wide approach rather than hypothesis-driven experiments
In addition, evidence has been provided that Nrf2 silencing can sensitize colon cancer models to cell death induced by anti-tumour agents [88]
Regulatory and commercial factors rather than safety concerns explain this limitation
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