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Using them concurrently creates a biological tug-of-war that makes it impossible to predict the net effect

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While that is part of the answer, new research points to a bigger mechanism at play

10.1002/sctm.18-0084 15 Camacho-AguilarE.YoonS

Pickrell and Youle, 2015)

Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties