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Even low levels of endotoxin contamination can trigger unintended inflammatory signalling in cell-based assays, significantly confounding results

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Rumore, PharmD, JD, MS, LLM, FAPhA is Of Counsel at Health Law Alliance and a registered U.S

Genetic or pharmacological inhibition of GCH1 leads to BH4 deficiency, driving cells toward peroxisome accumulation and ferroptosis [65]

doi:10.1016/j.wneu.2012.09.008 87

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