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Abbreviations B.P.: Blood pressure NA: Network analysis BA: Betulinic acid DA: Dihydrogathic acid HQ: Hydroquinidine TPC: Total phenolic content TFC: Total flavonoid content GAE/g: Gallic acid equivalent per gram SYR: Syringaresinol DPPH: 2,2-Diphenyl-1-picrylhydrayl ABTS: 2,2-Azino-bis-3-ethylbenzothia-zoline-6-sulphonic acid GI: Gastrointestinal AE: Aqueous extract ME: Methanolic extract DNA: Deoxyribonucleic acid H 2 O 2 : Hydrogen peroxide XXO: Xanthine oxidase STZ: Streptozocin LDL: Low density lipoprotein HDL: High density lipoprotein SOD: Superoxide dismutase CAT: Catalase GR: Glutathione reductase MAPK: Mitogen-activated protein kinase ROS: Reactive oxygen species NF- B: Nuclear factor kappa B Bcl-2: B-cell lymphoma 2 Bax: Bcl-2 Associated X-protein Bcl-XL: B-cell lymphoma-extra large ADAM: A Disintegrin and metalloproteinase HeLa: Henrietta lacks HAEC: Human aortic endothelial cells TNF-: Tumour necrosis factor References Adhimoolam K, Sureshbabu A, Smirnova E et al (2024) -Sitosteroldietary sources and role in cancer and diabetes management

Conflict of Interest The authors declare that they have no conflict of interest

How IV Glutathione Differs from Oral Supplements Absorption Matters Oral supplements pass through the digestive system, where much of the glutathione is broken down before absorption

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A Suggested Rotation Schedule Here's a practical 8-week rotation schedule: Week 1: Abdomen, right of navel Week 2: Abdomen, left of navel Week 3: Right thigh, outer side Week 4: Left thigh, outer side Week 5: Abdomen, right of navel (slightly higher position) Week 6: Abdomen, left of navel (slightly higher position) Week 7: Right thigh, outer side (different location) Week 8: Left thigh, outer side (different location) After this, you can repeat the cycle

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