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In HG-induced human glomerular mesangial cells and HFD/STZ-induced C57BL/6 mouse models, erythropoietin (EPO) activates PINK1/Parkin-mediated mitophagy, reduces ROS levels, improves renal function in DN mice, and reduces apoptosis of human glomerular mesangial cells [147]
Patients choosing sublingual drops should understand that dosing protocols differ from injectable schedules, and their provider should specify the appropriate titration for this delivery method
We found a significant fold increase in the levels of several tumor suppressor and DNA repair gene protein products (GP)s at the end of 4th week during 4-week intermittent fasting (CALU, INTS6, KIT, CROCC, PIGR), and 1 week after 4-week intermittent fasting (CALU, CALR, IGFBP4, SEMA4B) compared with the levels before 4-week intermittent fasting
I., Fichman, Y
Dysphagia 30 , 489495 (2015)