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Increased tight junctional permeability is associated with the development of colon cancer

It is most commonly administered via subcutaneous injection

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Its effective in animal models of inflammatory bowel disease (IBD), ulcerative colitis, and fistulas

The hCTR cells were cultured in growth medium consisting of Dulbeccos Modified Eagles Medium (DMEM, Gibco, #31966-021) supplemented with 10% v/v foetal bovine serum (FBS, Gibco, #16140-071), 1% v/v Penicillin-Streptomycin (Gibco, #15140-122), 0.6 mg/mL Geneticin G418 (Gibco, #10131-027) and 0.2 mg/mL Hygromycin (Invitrogen, #10687010)

We used logistic regression adjusted for age, sex, stroke severity, antiplatelet treatment and symptom onset to treatment time to evaluate the associations between IVT and sICH (defined as clinical deterioration due to new intracerebral hemorrhage within 7 days) and functional outcome at 6 months, measured by the Oxford Handicap Scale