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doi: 10.1016/j.redox.2021.101930 305 ZhangQ.XiangR.HuoS.ZhouY.JiangS.WangQ.et al

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Preclinical research exploring these exact receptor-binding mechanisms is conducted using reference compounds such as GLP-1S, a synthetic long-acting GLP-1 receptor agonist for laboratory use , which models GLP-1 pathway signaling in controlled in vitro and in vivo research settings

When the concentrations detected by three-phase HF-LPME were used to fit the correlations between the concentration and immobilization ratio, the correlation significantly improved compared to that using the nominal concentration, independent of the solution pH, suggesting that three-phase HF-LPME is a useful tool for estimating the toxicity of sulfadiazine and perhaps other weakly acidic organic compounds, independent of the solution pH