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Rapid tapering of Hydrocodone Bitartrate and Acetaminophen Tablets in a patient physically dependent on opioids may lead to a withdrawal syndrome and return of pain [see DOSAGE AND ADMINISTRATION, DRUG ABUSE AND DEPENDENCE]

GLP-1 can stimulate insulin secretion from islet cells, enhance insulin sensitivity and maintain dynamic balance of blood glucose

M., Al-Regaiey, K

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Both peptides are generally considered well-tolerated in preclinical studies, but mild injection-site reactions, nausea, dizziness, or rare allergic responses have been reported