49, 623647.10.1093/jexbot/49.329.1895 45 NoctorG.ArisiA
Hormonal changes are characterized mainly by a reduction of the biosynthesis of testicular inhibin B by Sertoli cells with increased secretion of follicle stimulating hormone (FSH) [61]
The supplement of glutathione with milk thistle extract and alpha-lipoic acid is even more effective for the liver and detox
10.1016/s0168-8278(01)00192-1 J Hepatol
Graphical Abstract Similar content being viewed by others Abbreviations DLAT : Dihydrolipoamide S-acetyltransferase FDX1: Ferredoxin 1 GCLC: Glutamate-cysteine ligase catalytic subunit ICB: Immune checkpoint blockade ICD: Immunogenic cell death L-BSO: L-Buthionine-(S,R)-sulfoximine LIAS: Lipoic acid synthetase SLC31A1: Solute carrier family 31 TIME: Tumor immune microenvironment TNBC: Triple-negative breast cancer Funding This work was supported by the National Key Clinical Specialty Construction Program, the Science and Technology Program of Chengdu (2024-YF05-00487-SN), the Science and Technology Program of Tibet Autonomous Region (XZ202401RK0005), the Sichuan Science and Technology program (2023YFS0133), the Natural Science Foundation of Xiamen Municipality (3502Z202374035)
The three major antioxidant enzymes are glutathione peroxidase (GPx), catalase (CAT) and the superoxide dismutase (SOD) [39]