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Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats

Among these products, liposomal systems and polymer-drug conjugates are two of the most important groups, and many other formulations are under clinical investigation, including chemotherapy, hyperthermia, radiation therapy, gene or RNA interference (RNAi) therapy, and immunotherapy (Wicki et al., 2015)

Holick, M

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Its a direct pharmacological action

Future studies using melatonin-competent mice, genetic validation of receptor independence, and time-of-day dosing paradigms will be critical to determine whether the melatoninglutathione axis can be exploited therapeutically to treat asthma