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However, the level of nonresponse at each follow-up has the potential to threaten both external validity (i.e., reduces the generalizability of these findings to those who completed follow-up) and internal validity (i.e., if study drop-outs with worse nicotine replacement therapy uptake were more likely to be in the intervention, the intervention effect might be due to attrition rather than the intervention itself)

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At least three out of five people who try a cigarette become daily smokers At least 61 per cent of people who try their first cigarette become, at least temporarily, daily smokers, suggests an analysis of survey data by Queen Mary University of London