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COMMENTARY Extracts from Newport new non-menthol (green) cigarettes did not increase intracellular Ca 2+ levels, even at the lowest dilution tested (10, p=0.48, n=3), similar to Newport non-menthol Reserve (red) unflavored control cigarettes (Figure 2)

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and (6) estimating the mean risk function and the BPRF, calculating the ROS and categorizing smokingoutcome pairs using a star-rating scheme from 1 to 5