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Even though CRP and fibrinogen are both upregulated in response to IL-6 29 we only observed a moderate correlation between IL-6 and CRP levels (R = 0.381) and saw no significant ( p = 0.50) correlation with fibrinogen levels (R = 0.099), suggesting that other factors determine levels of these acute phase proteins

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Baldwin GC, Tashkin DP, Buckley DM, Park AN, Dubinett SM, Roth MD