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Persistent or severe symptoms should be evaluated by a dentist or healthcare provider

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To minimise risk of harms, the EAG recommends the following measures for prescribers: Recommend NVPs in closed systems and avoid open systems to minimise the risk of poisoning, addition of toxic/illegal substances and contamination

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Cardiovascular toxicity A study by PMI researchers showed that IQOS exposure had 18 times fewer inhibitory effects than CS on chemotaxis and trans-endothelial migration of human coronary arterial endothelial cells as a marker of cardiovascular health 27