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Numerous autophagy receptors are present on the mitochondrial outer membrane, containing microtubule-associated protein 1A/1B-light chain 3 (LC3)-interacting region domains that can directly bind to LC3 without ubiquitination, thereby initiating mitophagy (Lu et al., 2023)

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Effective enforcement of these laws, coupled with public education and awareness campaigns, is important to reduce the health risks connected with tobacco and nicotine consumption in India