Box plot Scatter plot D
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Increased levels of matrix metalloproteinase (MMP)890 and MMP1 messenger ribonucleic acid91in skin tissues, and higher circulating MMP9 levels81, 92 are found in smokers, resulting in enhanced extracellular matrix degradation, which could also be part of the mechanisms for the decrease of collagen
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Also, clinical research found a possible link between the topical use of essential oils and the onset of male gynecomastia, or the development of breast tissue, in prepubescent boys
Reumann MK, Schaefer J, Titz B